]> Creatis software - clitk.git/blobdiff - segmentation/clitkExtractLymphStationsFilter.txx
Attempt to manually adjust the layout of the overlay panel for fusion to minimize...
[clitk.git] / segmentation / clitkExtractLymphStationsFilter.txx
index 2172dae21b215823d61f01f88b8fb49a4cbe6a98..58f2991d348426b184c92a37c6c7baf93848399a 100644 (file)
@@ -52,18 +52,12 @@ ExtractLymphStationsFilter():
   SetBackgroundValue(0);
   SetForegroundValue(1);
 
-  // Station 8
-  SetDistanceMaxToAnteriorPartOfTheSpine(10);
-  MaskImagePointType p;
-  p[0] = 15; p[1] = 2; p[2] = 1;
-  SetEsophagusDiltationForAnt(p);
-  p[0] = 5; p[1] = 10; p[2] = 1;
-  SetEsophagusDiltationForRight(p);
-  SetFuzzyThresholdForS8(0.5);
-
-  // Station 7
-  SetFuzzyThreshold(0.5);
-  SetStation7Filename("station7.mhd");
+  // Default values
+  ExtractStation_8_SetDefaultValues();
+  ExtractStation_3P_SetDefaultValues();
+  ExtractStation_2RL_SetDefaultValues();
+  ExtractStation_3A_SetDefaultValues();
+  ExtractStation_7_SetDefaultValues();
 }
 //--------------------------------------------------------------------
 
@@ -78,48 +72,51 @@ GenerateOutputInformation() {
   m_Input = dynamic_cast<const ImageType*>(itk::ProcessObject::GetInput(0));
   m_Mediastinum = GetAFDB()->template GetImage <MaskImageType>("Mediastinum");
 
+  // Global supports for stations
+  StartNewStep("Supports for stations");
+  StartSubStep(); 
+  ExtractStationSupports();
+  StopSubStep();  
+
   // Extract Station8
   StartNewStep("Station 8");
   StartSubStep(); 
   ExtractStation_8();
   StopSubStep();
 
-  // Compute some interesting points in trachea
-  // ( ALTERNATIVE -> SKELETON ANALYSIS ? 
-  //    Pb : not sufficient for mostXX points ... ) 
+  // Extract Station3P
+  StartNewStep("Station 3P");
+  StartSubStep(); 
+  ExtractStation_3P();
+  StopSubStep();
 
-  /* ==> todo (but why ???)
-     ComputeTracheaCentroidsAboveCarina();
-     ComputeBronchusExtremaPointsBelowCarina();
+  // Extract Station2RL
+  /*
+    StartNewStep("Station 2RL");
+    StartSubStep(); 
+    ExtractStation_2RL();
+    StopSubStep();
   */
 
-  if (0) { // temporary suppress
-    // Extract Station7
-    StartNewStep("Station 7");
-    StartSubStep();
-    ExtractStation_7();
-    StopSubStep();
+  // Extract Station3A
+  StartNewStep("Station 3A");
+  StartSubStep(); 
+  ExtractStation_3A();
+  StopSubStep();
+
+  // Extract Station7
+  StartNewStep("Station 7");
+  StartSubStep();
+  ExtractStation_7();
+  StopSubStep();
 
+  if (0) { // temporary suppress
     // Extract Station4RL
     StartNewStep("Station 4RL");
     StartSubStep();
     //ExtractStation_4RL();
     StopSubStep();
   }
-
-
-  //
-  //  typedef clitk::BooleanOperatorLabelImageFilter<MaskImageType> BFilter;
-  //BFilter::Pointer merge = BFilter::New();  
-  // writeImage<MaskImageType>(m_Output, "ouput.mhd");
-  //writeImage<MaskImageType>(m_Working_Support, "ws.mhd");
-  /*merge->SetInput1(m_Station7);
-    merge->SetInput2(m_Station4RL); // support
-    merge->SetOperationType(BFilter::AndNot); CHANGE OPERATOR
-    merge->SetForegroundValue(4);
-    merge->Update();
-    m_Output = merge->GetOutput();
-  */
 }
 //--------------------------------------------------------------------
 
@@ -129,7 +126,7 @@ template <class TImageType>
 void 
 clitk::ExtractLymphStationsFilter<TImageType>::
 GenerateInputRequestedRegion() {
-  DD("GenerateInputRequestedRegion (nothing?)");
+  //DD("GenerateInputRequestedRegion (nothing?)");
 }
 //--------------------------------------------------------------------
 
@@ -139,8 +136,6 @@ template <class TImageType>
 void 
 clitk::ExtractLymphStationsFilter<TImageType>::
 GenerateData() {
-  DD("GenerateData, graft output");
-
   // Final Step -> graft output (if SetNthOutput => redo)
   this->GraftOutput(m_ListOfStations["8"]);
 }
@@ -149,23 +144,98 @@ GenerateData() {
 
 //--------------------------------------------------------------------
 template <class TImageType>
-void 
+bool 
+clitk::ExtractLymphStationsFilter<TImageType>::
+CheckForStation(std::string station) 
+{
+  // Compute Station name
+  std::string s = "Station"+station;
+  
+
+  // Check if station already exist in DB
+  bool found = false;
+  if (GetAFDB()->TagExist(s)) {
+    m_ListOfStations[station] = GetAFDB()->template GetImage<MaskImageType>(s);
+    found = true;
+  }
+
+  // Define the starting support 
+  if (found && GetComputeStation(station)) {
+    std::cout << "Station " << station << " already exists, but re-computation forced." << std::endl;
+  }
+  if (!found || GetComputeStation(station)) {
+    m_Working_Support = m_Mediastinum = GetAFDB()->template GetImage<MaskImageType>("Mediastinum", true);
+    return true;
+  }
+  else {
+    std::cout << "Station " << station << " found. I used it" << std::endl;
+    return false;
+  }
+}
+//--------------------------------------------------------------------
+
+
+//--------------------------------------------------------------------
+template <class TImageType>
+bool
+clitk::ExtractLymphStationsFilter<TImageType>::
+GetComputeStation(std::string station) 
+{
+  return (m_ComputeStationMap.find(station) != m_ComputeStationMap.end());
+}
+//--------------------------------------------------------------------
+
+
+//--------------------------------------------------------------------
+template <class TImageType>
+void
 clitk::ExtractLymphStationsFilter<TImageType>::
-ExtractStation_8() {
+AddComputeStation(std::string station) 
+{
+  m_ComputeStationMap[station] = true;
+}
+//--------------------------------------------------------------------
 
-  // Check if m_ListOfStations["8"] exist. If yes -> use it as initial
-  // support instead of m_Mediastinum
-  if (m_ListOfStations["8"]) {
-    DD("Station 8 support already exist -> use it");
-    m_Working_Support = m_ListOfStations["8"];
+
+//--------------------------------------------------------------------
+template <class TImageType>
+void 
+clitk::ExtractLymphStationsFilter<TImageType>::
+ExtractStation_3P()
+{
+  if (CheckForStation("3P")) {
+    ExtractStation_3P_SI_Limits();
+    ExtractStation_3P_Ant_Limits();
+    ExtractStation_3P_Post_Limits();
+    ExtractStation_3P_LR_sup_Limits();
+    //    ExtractStation_3P_LR_sup_Limits_2();
+    ExtractStation_3P_LR_inf_Limits();
+    ExtractStation_8_Single_CCL_Limits(); // YES 8 !
+    ExtractStation_3P_Remove_Structures(); // after CCL
+    // Store image filenames into AFDB 
+    writeImage<MaskImageType>(m_ListOfStations["3P"], "seg/Station3P.mhd");
+    GetAFDB()->SetImageFilename("Station3P", "seg/Station3P.mhd"); 
+    WriteAFDB(); 
   }
-  else m_Working_Support = m_Mediastinum;
+}
+//--------------------------------------------------------------------
 
-  ExtractStation_8_SI_Limits();
-  ExtractStation_8_Post_Limits();
-  ExtractStation_8_Ant_Limits();
-  ExtractStation_8_LR_Limits();
-  // ExtractStation_8_LR_Limits();
+
+//--------------------------------------------------------------------
+template <class TImageType>
+void 
+clitk::ExtractLymphStationsFilter<TImageType>::
+ExtractStation_3A()
+{
+  if (CheckForStation("3A")) {
+    ExtractStation_3A_SI_Limits();
+    ExtractStation_3A_Ant_Limits();
+    ExtractStation_3A_Post_Limits();
+    // Store image filenames into AFDB 
+    writeImage<MaskImageType>(m_ListOfStations["3A"], "seg/Station3A.mhd");
+    GetAFDB()->SetImageFilename("Station3A", "seg/Station3A.mhd"); 
+    WriteAFDB(); 
+  }
 }
 //--------------------------------------------------------------------
 
@@ -174,15 +244,24 @@ ExtractStation_8() {
 template <class TImageType>
 void 
 clitk::ExtractLymphStationsFilter<TImageType>::
-ExtractStation_7() {
-  if (m_ListOfStations["7"]) {
-    DD("Station 7 support already exist -> use it");
-    m_Working_Support = m_ListOfStations["7"];
+ExtractStation_2RL()
+{
+  if (CheckForStation("2RL")) {
+    ExtractStation_2RL_SI_Limits();
+    ExtractStation_2RL_Post_Limits();
+    ExtractStation_2RL_Ant_Limits2();
+    ExtractStation_2RL_Ant_Limits(); 
+    ExtractStation_2RL_LR_Limits(); 
+    ExtractStation_2RL_Remove_Structures(); 
+    ExtractStation_2RL_SeparateRL(); 
+    
+    // Store image filenames into AFDB 
+    writeImage<MaskImageType>(m_ListOfStations["2R"], "seg/Station2R.mhd");
+    writeImage<MaskImageType>(m_ListOfStations["2L"], "seg/Station2L.mhd");
+    GetAFDB()->SetImageFilename("Station2R", "seg/Station2R.mhd"); 
+    GetAFDB()->SetImageFilename("Station2L", "seg/Station2L.mhd"); 
+    WriteAFDB(); 
   }
-  else m_Working_Support = m_Mediastinum;
-  ExtractStation_7_SI_Limits();
-  ExtractStation_7_RL_Limits();
-  ExtractStation_7_Posterior_Limits();
 }
 //--------------------------------------------------------------------
 
@@ -192,6 +271,8 @@ template <class TImageType>
 void 
 clitk::ExtractLymphStationsFilter<TImageType>::
 ExtractStation_4RL() {
+  DD("TODO");
+  exit(0);
   /*
     WARNING ONLY 4R FIRST !!! (not same inf limits)
   */    
@@ -202,73 +283,221 @@ ExtractStation_4RL() {
 //--------------------------------------------------------------------
 
 
+//--------------------------------------------------------------------
+template <class ImageType>
+void 
+clitk::ExtractLymphStationsFilter<ImageType>::
+Remove_Structures(std::string station, std::string s)
+{
+  try {
+    StartNewStep("[Station"+station+"] Remove "+s);  
+    MaskImagePointer Structure = GetAFDB()->template GetImage<MaskImageType>(s);
+    clitk::AndNot<MaskImageType>(m_Working_Support, Structure, GetBackgroundValue());
+  }
+  catch(clitk::ExceptionObject e) {
+    std::cout << s << " not found, skip." << std::endl;
+  }
+}
+//--------------------------------------------------------------------
+
+
 //--------------------------------------------------------------------
 template <class TImageType>
 void 
 clitk::ExtractLymphStationsFilter<TImageType>::
-FindExtremaPointsInBronchus(MaskImagePointer input, 
-                           int direction,
-                           double distance_max_from_center_point, 
-                           ListOfPointsType & LR, 
-                           ListOfPointsType & Ant, 
-                           ListOfPointsType & Post)
+SetFuzzyThreshold(std::string station, std::string tag, double value)
 {
+  m_FuzzyThreshold[station][tag] = value;
+}
+//--------------------------------------------------------------------
 
-  // Other solution ==> with auto bounding box ! (but pb to prevent to
-  // be too distant from the center point
 
-  // Extract slices
-  std::vector<typename MaskSliceType::Pointer> slices;
-  clitk::ExtractSlices<MaskImageType>(input, 2, slices);
+//--------------------------------------------------------------------
+template <class TImageType>
+double 
+clitk::ExtractLymphStationsFilter<TImageType>::
+GetFuzzyThreshold(std::string station, std::string tag)
+{
+  if (m_FuzzyThreshold.find(station) == m_FuzzyThreshold.end()) {
+    clitkExceptionMacro("Could not find options for station "+station+" in the list (while searching for tag "+tag+").");
+    return 0.0;
+  }
+
+  if (m_FuzzyThreshold[station].find(tag) == m_FuzzyThreshold[station].end()) {
+    clitkExceptionMacro("Could not find options "+tag+" in the list of FuzzyThreshold for station "+station+".");
+    return 0.0;
+  }
   
-  // Loop on slices
-  bool found;
-  for(uint i=0; i<slices.size(); i++) {
-    /*
-    // Keep main CCL
-    slices[i] = Labelize<MaskSliceType>(slices[i], 0, true, 10);
-    slices[i] = KeepLabels<MaskSliceType>(slices[i], 
-                                         GetBackgroundValue(), 
-                                         GetForegroundValue(), 1, 1, true);
-    */
+  return m_FuzzyThreshold[station][tag]; 
+}
+//--------------------------------------------------------------------
 
-    // ------- Find rightmost or leftmost point  ------- 
-    MaskSliceType::PointType LRMost;
-    found = 
-      clitk::FindExtremaPointInAGivenDirection<MaskSliceType>(slices[i], 
-                                                              GetBackgroundValue(), 
-                                                              0, // axis XY
-                                                              (direction==0?false:true),  // right or left according to direction
-                                                              LRMost);
-    // ------- Find postmost point  ------- 
-    MaskSliceType::PointType postMost;
-    found = 
-      clitk::FindExtremaPointInAGivenDirection<MaskSliceType>(slices[i], 
-                                                              GetBackgroundValue(), 
-                                                              1, false, LRMost, 
-                                                              distance_max_from_center_point, 
-                                                              postMost);
-    // ------- Find antmost point  ------- 
-    MaskSliceType::PointType antMost;
-    found = 
-      clitk::FindExtremaPointInAGivenDirection<MaskSliceType>(slices[i], 
+
+//--------------------------------------------------------------------
+template <class TImageType>
+void
+clitk::ExtractLymphStationsFilter<TImageType>::
+FindLineForS7S8Separation(MaskImagePointType & A, MaskImagePointType & B)
+{
+  // Create line from A to B with
+  // A = upper border of LLL at left
+  // B = lower border of bronchus intermedius (BI) or RightMiddleLobeBronchus
+  
+  try {
+    GetAFDB()->GetPoint3D("LineForS7S8Separation_Begin", A); 
+    GetAFDB()->GetPoint3D("LineForS7S8Separation_End", B);
+  }
+  catch(clitk::ExceptionObject & o) {
+    
+    DD("FindLineForS7S8Separation");
+    // Load LeftLowerLobeBronchus and get centroid point
+    MaskImagePointer LeftLowerLobeBronchus = 
+      GetAFDB()->template GetImage <MaskImageType>("LeftLowerLobeBronchus");
+    std::vector<MaskImagePointType> c;
+    clitk::ComputeCentroids<MaskImageType>(LeftLowerLobeBronchus, GetBackgroundValue(), c);
+    A = c[1];
+    
+    // Load RightMiddleLobeBronchus and get superior point (not centroid here)
+    MaskImagePointer RightMiddleLobeBronchus = 
+      GetAFDB()->template GetImage <MaskImageType>("RightMiddleLobeBronchus");
+    bool b = FindExtremaPointInAGivenDirection<MaskImageType>(RightMiddleLobeBronchus, 
                                                               GetBackgroundValue(), 
-                                                              1, true, LRMost, 
-                                                              distance_max_from_center_point, 
-                                                              antMost);
-    // Only add point if found
-    if (found)  {
-      // ------- Convert 2D to 3D points --------
-      MaskImageType::PointType p;
-      clitk::PointsUtils<MaskImageType>::Convert2DTo3D(LRMost, input, i, p);
-      LR.push_back(p); 
-      clitk::PointsUtils<MaskImageType>::Convert2DTo3D(antMost, input, i, p);
-      Ant.push_back(p);
-      clitk::PointsUtils<MaskImageType>::Convert2DTo3D(postMost, input, i, p);
-      Post.push_back(p);
+                                                              2, false, B);
+    if (!b) {
+      clitkExceptionMacro("Error while searching most superior point in RightMiddleLobeBronchus. Abort");
+    }
+    
+    // Insert into the DB
+    GetAFDB()->SetPoint3D("LineForS7S8Separation_Begin", A);
+    GetAFDB()->SetPoint3D("LineForS7S8Separation_End", B);
+  }
+}
+//--------------------------------------------------------------------
+
+
+//--------------------------------------------------------------------
+template <class TImageType>
+double 
+clitk::ExtractLymphStationsFilter<TImageType>::
+FindCarinaSlicePosition()
+{
+  double z;
+  try {
+    z = GetAFDB()->GetDouble("CarinaZ");
+  }
+  catch(clitk::ExceptionObject e) {
+    DD("FindCarinaSlicePosition");
+    // Get Carina
+    MaskImagePointer Carina = GetAFDB()->template GetImage<MaskImageType>("Carina");
+    
+    // Get Centroid and Z value
+    std::vector<MaskImagePointType> centroids;
+    clitk::ComputeCentroids<MaskImageType>(Carina, GetBackgroundValue(), centroids);
+
+    // We dont need Carina structure from now
+    Carina->Delete();
+    
+    // Put inside the AFDB
+    GetAFDB()->SetPoint3D("CarinaPoint", centroids[1]);
+    GetAFDB()->SetDouble("CarinaZ", centroids[1][2]);
+    WriteAFDB();
+    z = centroids[1][2];
+  }
+  return z;
+}
+//--------------------------------------------------------------------
+
+
+//--------------------------------------------------------------------
+template <class TImageType>
+void
+clitk::ExtractLymphStationsFilter<TImageType>::
+FindLeftAndRightBronchi()
+{
+  try {
+    m_RightBronchus = GetAFDB()->template GetImage <MaskImageType>("RightBronchus");
+    m_LeftBronchus = GetAFDB()->template GetImage <MaskImageType>("LeftBronchus");
+  }
+  catch(clitk::ExceptionObject & o) {
+
+    DD("FindLeftAndRightBronchi");
+    // The goal is to separate the trachea inferiorly to the carina into
+    // a Left and Right bronchus.
+  
+    // Get the trachea
+    MaskImagePointer Trachea = GetAFDB()->template GetImage<MaskImageType>("Trachea");
+
+    // Get the Carina position
+    m_CarinaZ = FindCarinaSlicePosition();
+
+    // Consider only inferiorly to the Carina
+    MaskImagePointer m_Working_Trachea = 
+      clitk::CropImageRemoveGreaterThan<MaskImageType>(Trachea, 2, m_CarinaZ, true, // AutoCrop
+                                                       GetBackgroundValue());
+
+    // Labelize the trachea
+    m_Working_Trachea = Labelize<MaskImageType>(m_Working_Trachea, 0, true, 1);
+
+    // Carina position must at the first slice that separate the two
+    // main bronchus (not superiorly). We thus first check that the
+    // upper slice is composed of at least two labels
+    MaskImagePointer RightBronchus;
+    MaskImagePointer LeftBronchus;
+    typedef itk::ImageSliceIteratorWithIndex<MaskImageType> SliceIteratorType;
+    SliceIteratorType iter(m_Working_Trachea, m_Working_Trachea->GetLargestPossibleRegion());
+    iter.SetFirstDirection(0);
+    iter.SetSecondDirection(1);
+    iter.GoToReverseBegin(); // Start from the end (because image is IS not SI)
+    int maxLabel=0;
+    while (!iter.IsAtReverseEndOfSlice()) {
+      while (!iter.IsAtReverseEndOfLine()) {    
+        if (iter.Get() > maxLabel) maxLabel = iter.Get();
+        --iter;
+      }
+      iter.PreviousLine();
     }
+    if (maxLabel < 2) {
+      clitkExceptionMacro("First slice from Carina does not seems to seperate the two main bronchus. Abort");
+    }
+
+    // Compute 3D centroids of both parts to identify the left from the
+    // right bronchus
+    std::vector<ImagePointType> c;
+    clitk::ComputeCentroids<MaskImageType>(m_Working_Trachea, GetBackgroundValue(), c);
+    ImagePointType C1 = c[1];
+    ImagePointType C2 = c[2];
+
+    ImagePixelType rightLabel;
+    ImagePixelType leftLabel;  
+    if (C1[0] < C2[0]) { rightLabel = 1; leftLabel = 2; }
+    else { rightLabel = 2; leftLabel = 1; }
+
+    // Select LeftLabel (set one label to Backgroundvalue)
+    RightBronchus = 
+      clitk::Binarize<MaskImageType>(m_Working_Trachea, rightLabel, rightLabel, 
+                                     GetBackgroundValue(), GetForegroundValue());
+    /*
+      SetBackground<MaskImageType, MaskImageType>(m_Working_Trachea, m_Working_Trachea, 
+      leftLabel, GetBackgroundValue(), false);
+    */
+    LeftBronchus = clitk::Binarize<MaskImageType>(m_Working_Trachea, leftLabel, leftLabel, 
+                                                  GetBackgroundValue(), GetForegroundValue());
+    /*
+      SetBackground<MaskImageType, MaskImageType>(m_Working_Trachea, m_Working_Trachea, 
+      rightLabel, GetBackgroundValue(), false);
+    */
+
+    // Crop images
+    RightBronchus = clitk::AutoCrop<MaskImageType>(RightBronchus, GetBackgroundValue()); 
+    LeftBronchus = clitk::AutoCrop<MaskImageType>(LeftBronchus, GetBackgroundValue()); 
+
+    // Insert int AFDB if need after 
+    GetAFDB()->template SetImage <MaskImageType>("RightBronchus", "seg/rightBronchus.mhd", 
+                                                 RightBronchus, true);
+    GetAFDB()->template SetImage <MaskImageType>("LeftBronchus", "seg/leftBronchus.mhd", 
+                                                 LeftBronchus, true);
   }
-} 
+}
 //--------------------------------------------------------------------
 
 #endif //#define CLITKBOOLEANOPERATORLABELIMAGEFILTER_TXX