]> Creatis software - clitk.git/commitdiff
Add GateSimulation2Dicom tool
authortbaudier <thomas.baudier@creatis.insa-lyon.fr>
Mon, 15 May 2017 13:33:00 +0000 (15:33 +0200)
committertbaudier <thomas.baudier@creatis.insa-lyon.fr>
Mon, 15 May 2017 13:33:00 +0000 (15:33 +0200)
tools/CMakeLists.txt
tools/clitkGateSimulation2Dicom.cxx [new file with mode: 0644]
tools/clitkGateSimulation2Dicom.ggo [new file with mode: 0644]
tools/clitkGateSimulation2DicomGenericFilter.cxx [new file with mode: 0644]
tools/clitkGateSimulation2DicomGenericFilter.h [new file with mode: 0644]
tools/clitkGateSimulation2DicomGenericFilter.txx [new file with mode: 0644]

index f2cc79c4c72fe2b18f53b435bc5f8f63f07ca456..96330d7998feefae7e112fba024d296a5fb8b4f8 100644 (file)
@@ -99,6 +99,16 @@ if(CLITK_BUILD_TOOLS)
   target_link_libraries(clitkWriteDicomSeries clitkCommon )
   set(TOOLS_INSTALL ${TOOLS_INSTALL} clitkWriteDicomSeries)
 
+  WRAP_GGO(clitkGateSimulation2Dicom_GGO_C clitkGateSimulation2Dicom.ggo)
+  add_executable(clitkGateSimulation2Dicom clitkGateSimulation2Dicom.cxx ${clitkGateSimulation2Dicom_GGO_C})
+  target_link_libraries(clitkGateSimulation2Dicom clitkCommon )
+  set(TOOLS_INSTALL ${TOOLS_INSTALL} clitkGateSimulation2Dicom)
+  
+  WRAP_GGO(clitkImage2DicomSeries_GGO_C clitkImage2DicomSeries.ggo)
+  add_executable(clitkImage2DicomSeries clitkImage2DicomSeries.cxx ${clitkImage2DicomSeries_GGO_C})
+  target_link_libraries(clitkImage2DicomSeries clitkCommon )
+  set(TOOLS_INSTALL ${TOOLS_INSTALL} clitkImage2DicomSeries)
+
   WRAP_GGO(clitkMedianTemporalDimension_GGO_C clitkMedianTemporalDimension.ggo)
   add_executable(clitkMedianTemporalDimension clitkMedianTemporalDimension.cxx
     ${clitkMedianTemporalDimension_GGO_C})
@@ -187,11 +197,11 @@ if(CLITK_BUILD_TOOLS)
   target_link_libraries(clitkDicomRTStruct2Image clitkDicomRTStruct)
   set(TOOLS_INSTALL ${TOOLS_INSTALL} clitkDicomRTStruct2Image)
 
-  if(CLITK_USE_SYSTEM_GDCM)
+  #if(CLITK_USE_SYSTEM_GDCM)
     WRAP_GGO(clitkImage2DicomRTStruct_GGO_C clitkImage2DicomRTStruct.ggo)
     add_executable(clitkImage2DicomRTStruct clitkImage2DicomRTStruct.cxx ${clitkImage2DicomRTStruct_GGO_C})
     target_link_libraries(clitkImage2DicomRTStruct clitkDicomRTStruct)
-  endif()
+  #endif()
 
   WRAP_GGO(clitkComposeVF_GGO_C clitkComposeVF.ggo)
   add_executable(clitkComposeVF clitkComposeVFGenericFilter.cxx clitkComposeVF.cxx ${clitkComposeVF_GGO_C})
diff --git a/tools/clitkGateSimulation2Dicom.cxx b/tools/clitkGateSimulation2Dicom.cxx
new file mode 100644 (file)
index 0000000..bf9cc01
--- /dev/null
@@ -0,0 +1,53 @@
+/*=========================================================================
+  Program:   vv                     http://www.creatis.insa-lyon.fr/rio/vv
+
+  Authors belong to:
+  - University of LYON              http://www.universite-lyon.fr/
+  - Léon Bérard cancer center       http://www.centreleonberard.fr
+  - CREATIS CNRS laboratory         http://www.creatis.insa-lyon.fr
+
+  This software is distributed WITHOUT ANY WARRANTY; without even
+  the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR
+  PURPOSE.  See the copyright notices for more information.
+
+  It is distributed under dual licence
+
+  - BSD        See included LICENSE.txt file
+  - CeCILL-B   http://www.cecill.info/licences/Licence_CeCILL-B_V1-en.html
+===========================================================================**/
+
+/* =================================================
+ * @file   clitkGateSimulation2Dicom.cxx
+ * @author Jef Vandemeulebroucke
+ * @date   4th of August
+ *
+ * @brief Write a volume into a dicom with the header of another dicom
+ *
+ ===================================================*/
+
+
+// clitk
+#include "clitkGateSimulation2Dicom_ggo.h"
+#include "clitkIO.h"
+#include "clitkGateSimulation2DicomGenericFilter.h"
+#include "clitkCommon.h"
+
+//--------------------------------------------------------------------
+int main(int argc, char * argv[])
+{
+
+  // Init command line
+  GGO(clitkGateSimulation2Dicom, args_info);
+  CLITK_INIT;
+
+  // Filter
+  typedef clitk::GateSimulation2DicomGenericFilter<args_info_clitkGateSimulation2Dicom> FilterType;
+  FilterType::Pointer genericFilter = FilterType::New();
+
+  genericFilter->SetArgsInfo(args_info);
+  genericFilter->Update();
+
+  return EXIT_SUCCESS;
+}// end main
+
+//--------------------------------------------------------------------
diff --git a/tools/clitkGateSimulation2Dicom.ggo b/tools/clitkGateSimulation2Dicom.ggo
new file mode 100644 (file)
index 0000000..563fb3d
--- /dev/null
@@ -0,0 +1,17 @@
+#File clitkGateSimulation2Dicom.ggo
+package "clitkGateSimulation2Dicom"
+version "1.0"
+purpose ""
+
+option "config"                -       "Config file"                     string        no
+option "verbose"       v       "Verbose"                         flag          off
+
+option "input"         i       "Input image filename"            string        yes
+option "inputDir"      d       "Input dicom directory"           string        yes
+option "outputDir"     o       "Output dicom directory"          string        yes 
+option "key"           k       "Keys of tags to modify"          string        no multiple default="0008|103e"
+option "tag"           t       "Tags values"                    string         no multiple default="MIDPOSITION"
+option "newSeriesUID"          e       "Write the series with a new series UID (ignored if given in key/tag option)"   flag    off
+option "newStudyUID"           u       "Write the series with a new study UID (ignored if given in key/tag option; forces newSeriesUID = true)"        flag    off
+option "useSizeAsReference"            s       "Use the size of the dicom image as reference for an occasional resampling"     flag    off
+option "preserve"              p       "Preserve private tags and keep original UID (eg: Xio)" flag    off
diff --git a/tools/clitkGateSimulation2DicomGenericFilter.cxx b/tools/clitkGateSimulation2DicomGenericFilter.cxx
new file mode 100644 (file)
index 0000000..e7cdd2f
--- /dev/null
@@ -0,0 +1,39 @@
+/*=========================================================================
+  Program:   vv                     http://www.creatis.insa-lyon.fr/rio/vv
+
+  Authors belong to:
+  - University of LYON              http://www.universite-lyon.fr/
+  - Léon Bérard cancer center       http://www.centreleonberard.fr
+  - CREATIS CNRS laboratory         http://www.creatis.insa-lyon.fr
+
+  This software is distributed WITHOUT ANY WARRANTY; without even
+  the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR
+  PURPOSE.  See the copyright notices for more information.
+
+  It is distributed under dual licence
+
+  - BSD        See included LICENSE.txt file
+  - CeCILL-B   http://www.cecill.info/licences/Licence_CeCILL-B_V1-en.html
+===========================================================================**/
+#ifndef clitkGateSimulation2DicomGenericFilter_cxx
+#define clitkGateSimulation2DicomGenericFilter_cxx
+
+/* =================================================
+ * @file   clitkGateSimulation2DicomGenericFilter.cxx
+ * @author
+ * @date
+ *
+ * @brief
+ *
+ ===================================================*/
+
+#include "clitkGateSimulation2DicomGenericFilter.h"
+
+
+namespace clitk
+{
+
+
+} //end clitk
+
+#endif  //#define clitkGateSimulation2DicomGenericFilter_cxx
diff --git a/tools/clitkGateSimulation2DicomGenericFilter.h b/tools/clitkGateSimulation2DicomGenericFilter.h
new file mode 100644 (file)
index 0000000..d495209
--- /dev/null
@@ -0,0 +1,121 @@
+/*=========================================================================
+  Program:   vv                     http://www.creatis.insa-lyon.fr/rio/vv
+
+  Authors belong to: 
+  - University of LYON              http://www.universite-lyon.fr/
+  - Léon Bérard cancer center       http://www.centreleonberard.fr
+  - CREATIS CNRS laboratory         http://www.creatis.insa-lyon.fr
+
+  This software is distributed WITHOUT ANY WARRANTY; without even
+  the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR
+  PURPOSE.  See the copyright notices for more information.
+
+  It is distributed under dual licence
+
+  - BSD        See included LICENSE.txt file
+  - CeCILL-B   http://www.cecill.info/licences/Licence_CeCILL-B_V1-en.html
+===========================================================================**/
+#ifndef clitkGateSimulation2DicomGenericFilter_h
+#define clitkGateSimulation2DicomGenericFilter_h
+
+/* =================================================
+ * @file   clitkGateSimulation2DicomGenericFilter.h
+ * @author 
+ * @date   
+ * 
+ * @brief 
+ * 
+ ===================================================*/
+
+
+// clitk include
+#include "clitkIO.h"
+#include "clitkImageCommon.h"
+#include "clitkGateSimulation2Dicom_ggo.h"
+
+//itk include
+#include "itkLightObject.h"
+#include "itkGDCMImageIO.h"
+#include "itkMetaDataDictionary.h"
+#include "itkGDCMSeriesFileNames.h"
+#include "itkImageSeriesReader.h"
+#include "itkImageSeriesWriter.h"
+#include "itkImageFileWriter.h"
+#include <vector>
+#include <itksys/SystemTools.hxx>
+
+namespace clitk 
+{
+  template<class args_info_type>
+  class ITK_EXPORT GateSimulation2DicomGenericFilter : public itk::LightObject
+  {
+  public:
+    //----------------------------------------
+    // ITK
+    //----------------------------------------
+    typedef GateSimulation2DicomGenericFilter   Self;
+    typedef itk::LightObject                          Superclass;
+    typedef itk::SmartPointer<Self>                   Pointer;
+    typedef itk::SmartPointer<const Self>             ConstPointer;
+   
+    // Method for creation through the object factory
+    itkNewMacro(Self);  
+
+    // Run-time type information (and related methods)
+    itkTypeMacro( GateSimulation2DicomGenericFilter, LightObject );
+
+
+    //----------------------------------------
+    // Typedefs
+    //----------------------------------------
+
+
+    //----------------------------------------
+    // Set & Get
+    //----------------------------------------    
+    void SetArgsInfo(const args_info_type & a)
+    {
+      m_ArgsInfo=a;
+      m_Verbose=m_ArgsInfo.verbose_flag;
+      m_InputFileName=m_ArgsInfo.input_arg;
+    }
+    
+    
+    //----------------------------------------  
+    // Update
+    //----------------------------------------  
+    void Update();
+
+  protected:
+
+    //----------------------------------------  
+    // Constructor & Destructor
+    //----------------------------------------  
+    GateSimulation2DicomGenericFilter();
+    ~GateSimulation2DicomGenericFilter() {};
+
+    
+    //----------------------------------------  
+    // Templated members
+    //----------------------------------------  
+    template <unsigned int Dimension>  void UpdateWithDim(std::string PixelType);
+    template <unsigned int Dimension, class PixelType>  void UpdateWithDimAndPixelType();
+
+
+    //----------------------------------------  
+    // Data members
+    //----------------------------------------
+    args_info_type m_ArgsInfo;
+    bool m_Verbose;
+    std::string m_InputFileName;
+
+  };
+
+
+} // end namespace clitk
+
+#ifndef ITK_MANUAL_INSTANTIATION
+#include "clitkGateSimulation2DicomGenericFilter.txx"
+#endif
+
+#endif // #define clitkGateSimulation2DicomGenericFilter_h
diff --git a/tools/clitkGateSimulation2DicomGenericFilter.txx b/tools/clitkGateSimulation2DicomGenericFilter.txx
new file mode 100644 (file)
index 0000000..ce1c1e3
--- /dev/null
@@ -0,0 +1,430 @@
+/*=========================================================================
+  Program:   vv                     http://www.creatis.insa-lyon.fr/rio/vv
+
+  Authors belong to:
+  - University of LYON              http://www.universite-lyon.fr/
+  - Léon Bérard cancer center       http://www.centreleonberard.fr
+  - CREATIS CNRS laboratory         http://www.creatis.insa-lyon.fr
+
+  This software is distributed WITHOUT ANY WARRANTY; without even
+  the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR
+  PURPOSE.  See the copyright notices for more information.
+
+  It is distributed under dual licence
+
+  - BSD        See included LICENSE.txt file
+  - CeCILL-B   http://www.cecill.info/licences/Licence_CeCILL-B_V1-en.html
+===========================================================================**/
+#ifndef clitkGateSimulation2DicomGenericFilter_txx
+#define clitkGateSimulation2DicomGenericFilter_txx
+
+/* =================================================
+ * @file   clitkGateSimulation2DicomGenericFilter.txx
+ * @author
+ * @date
+ *
+ * @brief
+ *
+ ===================================================*/
+
+// clitk
+#include "clitkResampleImageWithOptionsFilter.h"
+#if GDCM_MAJOR_VERSION >= 2
+#include "gdcmUIDGenerator.h"
+#else
+#include "gdcmFile.h"
+#include "gdcmUtil.h"
+#endif
+
+
+namespace clitk
+{
+
+
+//-----------------------------------------------------------
+// Constructor
+//-----------------------------------------------------------
+template<class args_info_type>
+GateSimulation2DicomGenericFilter<args_info_type>::GateSimulation2DicomGenericFilter()
+{
+  m_Verbose=false;
+  m_InputFileName="";
+}
+
+
+//-----------------------------------------------------------
+// Update
+//-----------------------------------------------------------
+template<class args_info_type>
+void GateSimulation2DicomGenericFilter<args_info_type>::Update()
+{
+  // Read the Dimension and PixelType
+  int Dimension;
+  std::string PixelType;
+  ReadImageDimensionAndPixelType(m_InputFileName, Dimension, PixelType);
+
+
+  // Call UpdateWithDim
+  if(Dimension==2) UpdateWithDim<2>(PixelType);
+  else if(Dimension==3) UpdateWithDim<3>(PixelType);
+  // else if (Dimension==4)UpdateWithDim<4>(PixelType);
+  else {
+    std::cout<<"Error, Only for 2 or 3  Dimensions!!!"<<std::endl ;
+    return;
+  }
+}
+
+//-------------------------------------------------------------------
+// Update with the number of dimensions
+//-------------------------------------------------------------------
+template<class args_info_type>
+template<unsigned int Dimension>
+void
+GateSimulation2DicomGenericFilter<args_info_type>::UpdateWithDim(std::string PixelType)
+{
+  if (m_Verbose) std::cout << "Image was detected to be "<<Dimension<<"D and "<< PixelType<<"..."<<std::endl;
+
+  if(PixelType == "short") {
+    if (m_Verbose) std::cout << "Launching filter in "<< Dimension <<"D and signed short..." << std::endl;
+    UpdateWithDimAndPixelType<Dimension, signed short>();
+  }
+  else if(PixelType == "unsigned_short"){
+    if (m_Verbose) std::cout  << "Launching filter in "<< Dimension <<"D and unsigned_short..." << std::endl;
+    UpdateWithDimAndPixelType<Dimension, unsigned short>();
+  }
+
+  else if (PixelType == "unsigned_char") {
+    if (m_Verbose) std::cout  << "Launching filter in "<< Dimension <<"D and unsigned_char..." << std::endl;
+    UpdateWithDimAndPixelType<Dimension, unsigned char>();
+  }
+
+  //     else if (PixelType == "char"){
+  //       if (m_Verbose) std::cout  << "Launching filter in "<< Dimension <<"D and signed_char..." << std::endl;
+  //       UpdateWithDimAndPixelType<Dimension, signed char>();
+  //     }
+  else if (PixelType == "double") {
+    if (m_Verbose) std::cout  << "Launching filter in "<< Dimension <<"D and double..." << std::endl;
+    UpdateWithDimAndPixelType<Dimension, double>();
+  }
+  else {
+    if (m_Verbose) std::cout  << "Launching filter in "<< Dimension <<"D and float..." << std::endl;
+    UpdateWithDimAndPixelType<Dimension, float>();
+  }
+}
+
+//-------------------------------------------------------------------
+// Update with the number of dimensions and the pixeltype read from
+// the dicom files. The MHD files may be resampled to match the
+// dicom spacing (and number of slices). Rounding errors in resampling
+// are handled by removing files when generating the output dicom
+// series.
+//-------------------------------------------------------------------
+template<class args_info_type>
+template <unsigned int Dimension, class  PixelType>
+void
+GateSimulation2DicomGenericFilter<args_info_type>::UpdateWithDimAndPixelType()
+{
+
+  // ImageTypes
+  typedef itk::Image<PixelType, Dimension> InputImageType;
+  typedef itk::Image<PixelType, Dimension> OutputImageType;
+
+  // Read the dicom directory
+  typedef itk::ImageSeriesReader< InputImageType >     ReaderType;
+  typedef itk::GDCMImageIO ImageIOType;
+  typedef itk::GDCMSeriesFileNames NamesGeneratorType;
+
+  ImageIOType::Pointer gdcmIO = ImageIOType::New();
+  NamesGeneratorType::Pointer namesGenerator = NamesGeneratorType::New();
+  namesGenerator->SetInputDirectory( m_ArgsInfo.inputDir_arg );
+  namesGenerator->SetOutputDirectory( m_ArgsInfo.outputDir_arg  );
+  typename   ReaderType::FileNamesContainer filenames_in = namesGenerator->GetInputFileNames();
+  typename   ReaderType::FileNamesContainer filenames_out = namesGenerator->GetOutputFileNames();
+
+  // Output the dicom files
+  unsigned int numberOfFilenames =  filenames_in.size();
+  if (m_Verbose) {
+    std::cout << numberOfFilenames <<" were read in the directory "<<m_ArgsInfo.inputDir_arg<<"..."<<std::endl<<std::endl;
+    for(unsigned int fni = 0; fni<numberOfFilenames; fni++) {
+      std::cout << "filename # " << fni << " = ";
+      std::cout << filenames_in[fni] << std::endl;
+    }
+  }
+
+  // Read the series
+  typename ReaderType::Pointer reader = ReaderType::New();
+  if (m_ArgsInfo.preserve_flag) {
+#if GDCM_MAJOR_VERSION >= 2
+    gdcmIO->LoadPrivateTagsOn();
+    gdcmIO->KeepOriginalUIDOn();
+#endif
+  }
+  reader->SetImageIO( gdcmIO );
+  reader->SetFileNames( filenames_in );
+  try {
+    reader->Update();
+  } catch (itk::ExceptionObject &excp) {
+    std::cerr << "Error: Exception thrown while reading the DICOM series!!" << std::endl;
+    std::cerr << excp << std::endl;
+  }
+
+  // Read the input (MHD file)
+  typedef typename InputImageType::RegionType RegionType;
+  typedef typename RegionType::SizeType SizeType;
+  typedef itk::ImageFileReader<InputImageType> InputReaderType;
+  typename InputReaderType::Pointer volumeReader = InputReaderType::New();
+  volumeReader->SetFileName( m_InputFileName);
+  volumeReader->Update();
+  
+  typename InputImageType::Pointer input = volumeReader->GetOutput();
+  if ((!m_ArgsInfo.useSizeAsReference_flag && (input->GetSpacing() != reader->GetOutput()->GetSpacing())) || 
+      (m_ArgsInfo.useSizeAsReference_flag && (input->GetLargestPossibleRegion().GetSize() != reader->GetOutput()->GetLargestPossibleRegion().GetSize()))) {
+        
+    // resampling is carried out on the fly if resolution or size between 
+    // the input mhd and input dicom series is different
+    
+    // Filter
+    typedef clitk::ResampleImageWithOptionsFilter<InputImageType, InputImageType> ResampleImageFilterType;
+    typename ResampleImageFilterType::Pointer filter = ResampleImageFilterType::New();
+    filter->SetInput(input);
+    filter->SetVerboseOptions(m_Verbose);
+    filter->SetGaussianFilteringEnabled(false);
+    filter->SetDefaultPixelValue(0);
+    
+    if (!m_ArgsInfo.useSizeAsReference_flag) {
+      filter->SetOutputSpacing(input->GetSpacing());
+      if (m_Verbose) {
+        std::cout << "Warning: The image spacing differs between the MHD file and the input dicom series. Performing resampling with default options using spacing as reference (for advanced options, use clitkResampleImage)." << std::endl;
+        std::cout << "MHD -> " << input->GetSpacing() << std::endl;
+        std::cout << "dicom -> " << reader->GetOutput()->GetSpacing() << std::endl;
+      }
+    }
+    else {
+      const SizeType& dicom_size = reader->GetOutput()->GetLargestPossibleRegion().GetSize();
+      SizeType output_size;
+      for (unsigned int i = 0; i < Dimension; i++)
+        output_size[i] = dicom_size[i];
+      filter->SetOutputSize(output_size);
+      if (m_Verbose) {
+          std::cout << "Warning: The image size differs between the MHD file and the input dicom series. Performing resampling with default options using size as reference (for advanced options, use clitkResampleImage)." << std::endl;
+          std::cout << "MHD -> " << input->GetLargestPossibleRegion().GetSize() << std::endl;
+          std::cout << "dicom -> " << reader->GetOutput()->GetLargestPossibleRegion().GetSize() << std::endl;
+      }
+    }
+
+    try {
+      filter->Update();
+      input = filter->GetOutput();
+    } catch( itk::ExceptionObject & excp ) {
+    std::cerr << "Error: Exception thrown while resampling!!" << std::endl;
+    std::cerr << excp << std::endl;
+    }
+  }
+    std::cout << "RESAMPING FILTER DONE" << std::endl;
+  
+  //   In some cases, due to resampling approximation issues, 
+  //   the number of slices in the MHD file may be different (smaller)
+  //   from the number of files in the template dicom directory. 
+  //   To avoid ITK generating an exception, we reduce the number 
+  //   of DCM files to be considered, and a warning is printed
+  //   in verbose mode
+  const RegionType volumeRegion = input->GetLargestPossibleRegion();
+  const SizeType& volumeSize = volumeRegion.GetSize();
+  if (m_Verbose) {
+    std::cout << volumeRegion << volumeSize << std::endl;
+  }
+    std::cout << Dimension << volumeSize[2] << numberOfFilenames << std::endl;
+  if (Dimension == 3 && volumeSize[2] < numberOfFilenames) {
+    if (m_Verbose)
+      std::cout << "Warning: The number of files in " << m_ArgsInfo.inputDir_arg << " (" << filenames_in.size() << " files) is greater than the number of slices in MHD (" << volumeSize[2] << " slices). Using only " << volumeSize[2] << " files." << std::endl;
+    
+    filenames_in.resize(volumeSize[2]);
+    filenames_out.resize(filenames_in.size());
+    numberOfFilenames =  filenames_in.size();
+  }
+
+  // Modify the meta dictionary
+  typedef itk::MetaDataDictionary   DictionaryType;
+  const std::vector<DictionaryType*>* dictionary = reader->GetMetaDataDictionaryArray();
+
+  // Get keys
+  unsigned int numberOfKeysGiven=m_ArgsInfo.key_given;
+    if (m_ArgsInfo.verbose_flag) 
+      DD(numberOfKeysGiven);
+
+  std::string seriesUID;
+  std::string frameOfReferenceUID;
+  std::string studyUID;
+  
+  // one pass through the keys given on the cmd-line, to check what will be recreated
+  std::string seriesUIDkey = "0020|000e";
+  std::string seriesNumberKey = "0020|0011";
+  std::string seriesDescriptionKey = "0008|103e";
+  std::string frameOfReferenceUIDKey = "0020|0052";
+  std::string studyUIDKey = "0020|000d";
+  std::string studyIDKey = "0020|0010";
+  std::string studyDescriptionKey = "0008|1030";
+  bool seriesUIDGiven = false;
+  bool seriesNumberGiven = false;
+  bool seriesDescriptionGiven = false;
+  bool studyUIDGiven = false;
+  bool studyIDGiven = false;
+  bool studyDescriptionGiven = false;
+  for (unsigned int i = 0; i < numberOfKeysGiven; i++) {
+    std::string entryId( m_ArgsInfo.key_arg[i] );
+    if (m_ArgsInfo.verbose_flag) 
+      DD(entryId);
+    
+    seriesUIDGiven |= (entryId ==  seriesUIDkey || entryId ==  frameOfReferenceUIDKey);
+    seriesNumberGiven |= (entryId == seriesNumberKey);
+    seriesDescriptionGiven |= (entryId == seriesDescriptionKey);
+    studyUIDGiven |= (entryId == studyUIDKey);
+    studyIDGiven |= (entryId == studyIDKey);
+    studyDescriptionGiven |= (entryId == studyDescriptionKey);
+  }
+
+  // force the creation of a new series if a new study was specified
+  if (!studyUIDGiven && m_ArgsInfo.newStudyUID_flag) {
+    m_ArgsInfo.newSeriesUID_flag = true;
+#if GDCM_MAJOR_VERSION >= 2
+    gdcm::UIDGenerator suid;
+    studyUID = suid.Generate();
+#else
+    studyUID = gdcm::Util::CreateUniqueUID( gdcmIO->GetUIDPrefix());
+#endif
+  }
+    
+  if (!seriesUIDGiven && m_ArgsInfo.newSeriesUID_flag) {
+#if GDCM_MAJOR_VERSION >= 2
+    gdcm::UIDGenerator suid;
+    seriesUID = suid.Generate();
+    gdcm::UIDGenerator fuid;
+    frameOfReferenceUID = fuid.Generate();
+#else
+    seriesUID = gdcm::Util::CreateUniqueUID( gdcmIO->GetUIDPrefix());
+    frameOfReferenceUID = gdcm::Util::CreateUniqueUID( gdcmIO->GetUIDPrefix());
+#endif
+  }
+
+  if (m_ArgsInfo.verbose_flag) {
+    DD(seriesUID);
+    DD(frameOfReferenceUID);
+    DD(studyUID);
+  }
+
+  // check if file UIDs will be be preserved
+  bool useInputFileUID = true;
+  if (m_ArgsInfo.newSeriesUID_flag || m_ArgsInfo.newStudyUID_flag || seriesUIDGiven || studyUIDGiven) {
+    useInputFileUID = false;
+  }
+  else {
+#if GDCM_MAJOR_VERSION < 2
+    gdcmIO->SetKeepOriginalUID(true);
+#endif
+    namesGenerator->SetOutputDirectory( m_ArgsInfo.outputDir_arg  );
+  }
+  
+  filenames_out.resize(numberOfFilenames);
+  
+  time_t t;
+  t = time(&t);
+  struct tm* instanceDateTimeTm = localtime(&t);
+  char datetime[16];
+  strftime(datetime, 16, "%Y%m%d", instanceDateTimeTm);
+  std::ostringstream instanceDate;
+  instanceDate << datetime;
+  std::ostringstream instanceTime;
+  strftime(datetime, 16, "%H%M%S", instanceDateTimeTm);
+  instanceTime << datetime;
+  
+  // update output dicom keys/tags
+  for(unsigned int fni = 0; fni<numberOfFilenames; fni++) {
+    for (unsigned int i = 0; i < numberOfKeysGiven; i++) {
+      std::string entryId(m_ArgsInfo.key_arg[i]  );
+      std::string value( m_ArgsInfo.tag_arg[i] );
+
+      itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), entryId, value );
+    }
+
+    // series UID
+    if (!seriesUIDGiven) {
+      if (m_ArgsInfo.newSeriesUID_flag) {
+        itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), seriesUIDkey, seriesUID );
+        itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), frameOfReferenceUIDKey, frameOfReferenceUID );
+      }
+    }
+    
+    // study UID
+    if (!studyUIDGiven) {
+      if (m_ArgsInfo.newStudyUID_flag) 
+        itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), studyUIDKey, studyUID );
+    }
+    
+    // study description
+    if (studyUIDGiven || m_ArgsInfo.newStudyUID_flag) {
+      if (!studyIDGiven)
+        itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), studyIDKey,itksys::SystemTools::GetFilenameName( m_ArgsInfo.outputDir_arg ));
+      if (!studyDescriptionGiven)
+        itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), studyDescriptionKey,itksys::SystemTools::GetFilenameName( m_ArgsInfo.outputDir_arg ));
+      
+      itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), "0008|0020", instanceDate.str() );
+      itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), "0008|0030", instanceTime.str() );
+    }
+    
+    // series description/number
+    if (seriesUIDGiven || m_ArgsInfo.newSeriesUID_flag) {
+      if (!seriesDescriptionGiven)
+        itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), seriesDescriptionKey, itksys::SystemTools::GetFilenameName(m_ArgsInfo.outputDir_arg) );
+      if (!seriesNumberGiven)
+        itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), seriesNumberKey, itksys::SystemTools::GetFilenameName(m_ArgsInfo.outputDir_arg) );
+
+      itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), "0008|0012", instanceDate.str() );
+      itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), "0008|0013", instanceTime.str() );
+    }
+
+    // file UIDs are recreated for new studies or series
+    if (!useInputFileUID)
+    {
+      if (m_ArgsInfo.verbose_flag)
+        std::cout << "Recreating file UIDs" << std::endl;
+
+      std::string fileUID;
+#if GDCM_MAJOR_VERSION >= 2
+      gdcm::UIDGenerator fid;
+      fileUID = fid.Generate();
+#else
+      fileUID = gdcm::Util::CreateUniqueUID( gdcmIO->GetUIDPrefix());
+#endif
+      itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), "0008|0018", fileUID );
+      itk::EncapsulateMetaData<std::string>( *((*dictionary)[fni]), "0002|0003", fileUID );
+      
+      filenames_out[fni] = itksys::SystemTools::CollapseFullPath(fileUID.c_str(), m_ArgsInfo.outputDir_arg) + std::string(".dcm"); 
+    }
+  }
+  
+  // Output directory and filenames
+  itksys::SystemTools::MakeDirectory( m_ArgsInfo.outputDir_arg ); // create if it doesn't exist
+  typedef itk::ImageFileWriter<OutputImageType>  SeriesWriterType;
+  typename SeriesWriterType::Pointer seriesWriter = SeriesWriterType::New();
+
+  seriesWriter->SetInput( input );
+  seriesWriter->SetImageIO( gdcmIO );
+  
+  seriesWriter->SetFileName( filenames_out[0] );
+  seriesWriter->SetMetaDataDictionary( *((*dictionary)[0]) );
+
+  // Write
+  try {
+    if (m_ArgsInfo.verbose_flag)
+      std::cout << seriesWriter << std::endl;
+    seriesWriter->Update();
+  } catch( itk::ExceptionObject & excp ) {
+    std::cerr << "Error: Exception thrown while writing the series!!" << std::endl;
+    std::cerr << excp << std::endl;
+  }
+
+}
+
+}//end clitk
+
+#endif //#define clitkGateSimulation2DicomGenericFilter_txx